JOURNAL OF LIAONING TECHNICAL UNIVERSITY
(NATURAL SCIENCE EDITION)
LIAONING GONGCHENG JISHU DAXUE XUEBAO (ZIRAN KEXUE BAN)
辽宁工程技术大学学报(自然科学版)
BREAST CANCER: THE KEY ROLE OF EARLY DETECTION IN ENHANCING CONTROL AND CARE
ADENIJI, Oluwabunmi Mercy, Prof. Rev. Sr. OGUNKORODE, Agatha Olufunk, Prof. OKAFOR, Uchendi Fidelis, OWOLABI, Wuraola Foluke
Abstract
This literature-based review provides a comprehensive examination of breast cancer research, focusing on epidemiology, pathogenesis, risk factors, early detection, and survival rates. A literature based search strategy was employed, utilizing databases such as PubMed, Google Scholar, Scopus, and Web of Science, with search terms including "breast cancer epidemiology," "risk factors," and "early detection methods." Studies published between 2000 and 2024 were selected based on rigorous inclusion criteria, including peer-reviewed articles, systematic reviews, and meta-analyses. The review synthesized data from selected studies, highlighting trends in incidence and mortality, the role of genetic factors like BRCA1 and HER2, and the impact of various risk factors, including age, family history, and lifestyle. It also evaluated the effectiveness of early detection methods, such as mammography and MRI, and analyzed survival rates in relation to early diagnosis and treatment advancements. The findings were integrated to offer a detailed overview of current knowledge on breast cancer, adhering to PRISMA guidelines. The review concludes with a discussion of implications for public health and clinical practice, identifying gaps and suggesting directions for future research.
Keywords: Breast Cancer, Epidemiological Data, Pathogenesis, Risk Factors, Early Detection