JOURNAL OF LIAONING TECHNICAL UNIVERSITY
(NATURAL SCIENCE EDITION)
LIAONING GONGCHENG JISHU DAXUE XUEBAO (ZIRAN KEXUE BAN)
辽宁工程技术大学学报（自然科学版）
A REVIEW OF FLAVONOIDS, BIOSYNTHESIS, SOURCES AND THEIR USE IN INFECTIOUS DISEASES
Muhammad Hassan Butt, Sadiah Saleem, Maria Manan, Muhammad Yasir Ali, Numera Arshad, Muhammad Ahmed Khan, Kamran Saeed Ahmad Qadri, Ahmad Nawaz, Anza Ahmad, Mohsin Ali, Ijaz Ali
Abstract
Flavonoids are the plant’s secondary metabolites and majority of them are effective medicinal agents. These flavonoids can improve human health when a person is afflicted with a variety of infectious diseases. Flavonoids are extensively employed in food, medicines, and nutraceuticals due to their safety and protective properties, which encompass antibacterial, antiviral, antifungal, and antiparasitic potential. The production of flavonoids from plants necessitates complex extraction processes and downstream handling with potentially dangerous compounds. Flavonoids are a diverse group of plant compounds that can be broken down into several main subgroups. These subgroups contain variety of compounds possessing many medicinal as well as anti-infection properties. This review will delve into the various subgroups of flavonoids, highlighting their diverse compounds and the wide array of medicinal and anti-infection properties they possess. We will summarize their sources, biosynthesis, mechanisms of action, and their application against infectious diseases, drawing upon previously reported studies.